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This article originally appeared in the April 2003 Women’s Health Watch and is provided courtesy of Harvard Health Publications.

The new ABCs of vitamin and mineral intake

The alphabet of essential micronutrients has changed, with important implications for our diet and use of supplements.

Marvel that it is, the body doesn’t manufacture enough of some 40 compounds that it needs for all of its life-sustaining tasks, from building bone, blood, and muscle to regulating brain, liver, and heart function. These essentials—called micronutrients because we need only tiny amounts of them—must come from the food, beverages, and supplements we consume. They include more than two dozen vitamins and minerals.

Official guidance on how much we need of each micronutrient has undergone a shift in emphasis since the federal government issued its first set of Recommended Dietary Allowances (RDAs) some 60 years ago. The original focus was on preventing deficiency diseases, such as scurvy (vitamin C deficiency) and beriberi (vitamin B1 deficiency). Since then, researchers have discovered that certain micronutrients help reduce the risk for major chronic disorders—such as atherosclerosis, cancer, and osteoporosis—if taken in doses higher than are required to prevent deficiency diseases. At the same time, we now know about ailments that can occur when people take overly high doses of supplements.

Making sense of alphabet soup
  DRI   RDA Recommended Dietary Allowance  
  AI   Adequate Intake  
  UL   Tolerable Upper Intake Level  
  DV   Daily Value  
  mcg   Micrograms  
  mg   Milligrams  
  IU   International Units  

With a new focus on the micronutrient levels needed for good health, scientists have recalculated the amounts of vitamins and minerals we need, raising some levels, lowering others, and identifying how much is too much. This effort has also led to changes in the terminology we use to talk about micronutrient intake.

Changing values, new designations
The Food and Nutrition Board of the National Academy of Sciences’ Institute of Medicine (the government’s adviser on health policy) recently completed a comprehensive new set of nutrient standards called Dietary Reference Intakes (DRIs). These reflect the latest evidence-based research on the links between micronutrients and health and replace the old RDAs.

For the changeover to DRIs, expert panels reexamined and, when necessary, revised the RDAs. If too little was known to establish an RDA, the scientists provided an adequate intake (AI) value. They also designated a tolerable upper intake level (UL), the highest amount of a nutrient deemed likely to have no harmful effects on most healthy people.

DRIs take into account varying nutritional needs by gender and at different stages of life—for example, during pregnancy and lactation, or as we age. As a result, the RDA (or AI) for any one vitamin or mineral may include varying amounts.

Labels: A different matter
You won’t find DRI designations used on food and supplement labels. Instead, labels indicate a percentage of what is called a “daily value” (DV) of a vitamin or mineral. DV is an FDA designation and is the level of intake that the FDA has determined the general American population needs each day. The “% DV” is the percentage of the micronutrient found in one serving.

DVs are not always the same as the new RDAs or AIs. For one thing, the FDA wants to keep labeling simple. It would be impractical, for example, to print multiple values (for pregnant or non-pregnant women, older women, men, and older men) for any one micronutrient. Also, the FDA has not yet updated its DVs to reflect the same new information that the National Academy of Sciences used to establish the DRIs. It plans to do so within the next few years.

The vitamins we need
Vitamins are either water-soluble or fat-soluble. The first group includes vitamin C and the B vitamins. Because water-soluble vitamins don’t store well in the body, we need to consume them on a regular basis. They present little risk of an overdose.

Vitamins in the fat-soluble group—A, D, E, and K—require some fat in the diet to permit them to be absorbed in the intestine. The body stores these vitamins in fat tissues and the liver, so we don’t need to consume them every day. But the one disadvantage of vitamin storage is that harmful levels can build up, especially through supplement use.

A well-balanced diet that includes fruits, vegetables, whole grains, and some dairy products is all that most people need to meet the DRIs. Yet maintaining a high-quality diet can be hard to do. It may be difficult to obtain the RDA of a vitamin through food alone. For example, women of childbearing age may not get adequate folic acid through food to reduce the risk of certain birth defects. And people over 50 may not absorb enough vitamin B12 from food. In light of these concerns, it makes sense to take a standard daily multivitamin as a backup.

See the chart, below, for the new DRIs for vitamins for women. And look for an update on mineral intakes in the May 2003 Harvard Women’s Health Watch.

Dietary reference intakes for women: Vitamins
Vitamin
Function / effects
Daily dose (RDA/AI)+
Tolerable Upper Intake Level (UL)+
Some food sources
Vitamin A (Retinoids — retinol, retinoic acid — are active forms. Beta carotene is converted to vitamin A in the body.) Required for vision, tissue and skin health, and immune function. Beta carotene and other carotenoids available in fruits and vegetables may help lower cataract and lung cancer risk. RDA: 700 mcg (2,333 IU), age 19 and over; 770 mcg (2,566 IU) during pregnancy; 1,300 mcg (4,333 IU) during lactation. 3,000 mcg/day (10,000 IU) Retinoids: beef, liver, eggs, shrimp, fish, fortified milk, and some cheeses. Beta carotene: sweet potatoes, carrots, squash, spinach, mangoes, and turnip greens.
Vitamin B1 (thiamin) Helps convert food into energy; needed for healthy skin, hair, muscles, and brain. RDA: 1.1 mg, age 19 and over; 1.4 mg during pregnancy and lactation. Enriched, fortified, or whole-grain products; breads; grains; cereals; pork; organ meats; legumes; nuts; and seeds.
Vitamin B2 (riboflavin) Helps convert food into energy; regulates hormones; needed for healthy skin, hair, blood, and brain. RDA: 1.1 mg, age 19 and over; 1.4 mg during pregnancy; 1.6 mg during lactation. Organ meats, milk products, and whole grains and fortified foods.
Vitamin B3 (niacin, nicotinic acid) Helps convert food into energy; helps maintain skin, blood cells, brain, and nervous system. RDA: 14 mg, age 19 and over; 18 mg during pregnancy; 17 mg during lactation. 35 mg/day * Meat, fish, poultry, enriched and whole gains, and fortified cereals.
Vitamin B5 (pantothenic acid) Helps convert food into energy; aids in production of lipids, neuro-transmitters, and hemoglobin. AI: 5 mg, age 19 and over; 6 mg during pregnancy; 7 mg during lactation. Many foods, including chicken, beef, oats, cereals, tomato products, liver, kidney, yeast, egg yolks, broccoli, and whole grains.
Vitamin B6 (pyridoxal, pyridoxine, pyridoxamine) Helps convert food into energy; aids in production of lipids, neuro-transmitters, and hemoglobin. AI: 5 mg, age 19 and over; 6 mg during pregnancy; 7 mg during lactation. Many foods, including chicken, beef, oats, cereals, tomato products, liver, kidney, yeast, egg yolks, broccoli, and whole grains.
Vitamin B12 (cobalamin) Aids in making new cells; protects nerve cells; prevents pernicious anemia; helps lower homocysteine levels. RDA: 2.4 mcg, age 19 and over; 2.6 mcg during pregnancy; 2.8 mcg during lactation. Fortified cereals, meat, fish, poultry, milk, cheese, and eggs.
Biotin Helps to convert food into energy, break down fats, and keep bones and hair healthy. AI: 30 mcg, age 19 and over and during pregnancy; 35 mcg during lactation. † Organ meats, whole grains, egg yolks, soybeans, and fish.
Vitamin C (ascorbic acid) An antioxidant that protects cells, promotes iron absorption, and aids in neuro-transmitter and collagen production. RDA: 75 mg, age 19 and over; 85 mg during pregnancy; 120 mg during lactation. (Smokers need an additional 35 mg/day.) 2,000 mg/day Citrus fruits, tomatoes, potatoes, broccoli, strawberries, Brussels sprouts, cauliflower, and spinach.
Choline Aids in brain and nerve activities; helps metabolize and transport fats. AI: 425 mg, age 19 and over; 450 mg during pregnancy; 550 mg during lactation. 3,500 mg/day Liver, milk, eggs, and peanuts.
Vitamin D (calciferol) Helps regulate calcium and phosphorus concentrations in the blood; helps form teeth and bones. AI: 5 mcg, age 19–50, during pregnancy, and during lactation; 10 mcg, age 51–70; 15 mcg, age 71 and over. 50 mcg (2,000 IU) Fatty fish, fish liver oils, fortified cereals, and fortified milk or margarine.
Vitamin E (alpha-tocopherol) An antioxidant that protects cells. RDA: 15 mg (22 IU from natural sources; 33 IU from synthetic sources of vitamin E), age 19 and over and during pregnancy; 19 mg during lactation. 1,000 mg/day (1,500 IU from natural vitamin E; 2,200 IU from synthetic) Vegetable oils, whole grains, nuts, fruits, wheat germ, and leafy green vegetables.
Folic acid (folate, folacin) Required for new cell creation; helps prevent brain and spine defects in the fetus; helps lower homocysteine levels; offsets breast cancer risk in women who consume alcohol. RDA: 400 mcg, age 19 and over; 600 mcg during pregnancy; 500 mcg during lactation. 1,000 mcg * Fortified grains and cereals, asparagus, spinach, turnip greens, orange juice, tomato juice, black-eyed peas, and chickpeas.
Vitamin K (phylloquinone, menadione) Aids in blood clotting and bone metabolism. AI: 90 mcg, age 19 and over, and during pregnancy and lactation. Deep green vegetables, Brussels sprouts, cabbage, milk, eggs, and margarine.
+ Recommended Dietary Allowance (RDA), Adequate Intake (AI), and Tolerable Upper Intake Level (UL) are designations and intake levels developed by the National Academy of Sciences Food and Nutrition Board.
† Not determined due to lack of data. Source should be food only, to prevent high levels of intake.
* Applies only to synthetic forms obtained from supplements and/or fortified foods.
Sources: Adapted from Dietary Reference Intakes: Vitamins, available as a PDF at
www.iom.edu/iom/iomhome.nsf/pages/Fnb+Dri?OpenDocument and The Benefits and Risks of Vitamins and Minerals: A Special Health Report from Harvard Medical School, Harvard Health Publications, 2003.

 

 
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