Starving cancer to death: Anti-angiogenesis aims to restrict the lifeblood of tumors
Cancer cells grow out of control, unaffected by the intricate network of signals that keeps normal cells in check. They do not respond to “stop” signals, dividing without any outside stimulus and without aging or dying. But even cancer cells require support from normal cells in the healthy tissues around them. Today researchers are working with a new class of cancer drugs designed to exploit this dependency. These therapies are just one part of the rapidly expanding inquiry into anti-angiogenesis and its applications in cancer treatment centers around the world. In this issue of HMI World, three researchers discuss the preventative and therapeutic potential of anti-angiogenesis processes, and explain the complexities associated with moving anti-angiogenesis from the laboratory to the clinic.

What do you think?
HMI World invites reader responses.

Executive summary: European health care leaders untangle the paradox of progress at HMI-Lausanne course
Designed to address specific challenges of health care leaders in Europe, course focuses on issues that are rapidly assuming international importance

Acibadem builds community of nurse leaders pivotal to patient and staff satisfaction
Workshop is part of an extensive initiative aimed at helping Acibadem’s three hospitals better meet their clinical requirements and address the nursing issues that plague health care organizations worldwide

Health care policymakers from Denmark explore emergency medical care during Boston visit

Dennis Ross-Degnan is fourth to receive Klaus Peter International Teaching Award

Conference organized by HMI and Hygeia Hospital focuses on preventive medicine

Exchange program offers students from Taiwan new perspectives on medical practice and instruction

Tokyo faculty continue curriculum development work at 10-day course in Boston

Founding members of WHARF faculty attend AIDS conference at Harvard-affiliated hospital

HMI and Dominican university collaborate on plans for new medical school

Embracing change—again and again and again—at the Harvard Macy Institute

Classic management cases and other insights from the business world help to cast new light on the values at the center of the medical mission

Upcoming courses
and events
Program for Caribbean Educators in the Health Sciences
St. Matthew’s University School of Medicine,
Grand Cayman
December 10-15, 2005
Deadline to appy:
September 30, 2005

Program for Educators in the Health Professions
January 8-18 and
May 21-26, 2006
Deadline to apply:
September 13, 2005

Messages for men at each stage of life
Harvard Men’s Health Watch

Making sense of multiple sclerosis
Harvard Women’s Health Watch

Heart disease: It’s partly in your head
Harvard Heart Letter

Clearing the air
Harvard Magazine

BWH researchers identify antigen for type 1 diabetes
Brigham & Women’s Hospital

''Brown fat'' cells hold clues for possible obesity treatments
Children’s Hospital

Diabetic retinopathy occurs in pre-diabetes
Massachusetts General Hospital

Left-or right-brain? Genes may tell the story
Beth Israel Deaconess Medical Center